Provide advanced nursing care including diagnosis, treatment, and prescribing medications. Median salary in Amarillo: $115K/year. Data from BLS, O*NET, and H-1B disclosures.
Figures represent annual base salary in Amarillo, Texas. Reviewed by SalaryOptics Editorial · How we calculate this →
Analysis derived from the salary, COL, tax, and labor-market figures above — specific to this role and city.
Nurse Practitioners in Amarillo earn approximately 5% lower than the US national median for this role — a $6,000 discount on annual base salary. Amarillo's lower wage level partially reflects the area's cost-of-living index of 82 (US avg = 100).
Adjusted for Amarillo's cost-of-living index (82), the median Nurse Practitioner salary buys the equivalent of $140,244 in a US-average-cost city. That's $19,244 more purchasing power than the national median — a meaningful real-wage advantage.
Texas has no state income tax, which is worth roughly $10,695 per year at this salary level compared to a California Nurse Practitioner on the same gross pay. A Amarillo Nurse Practitioner would need to earn $126,792 in California to net the same take-home.
Based on BLS 2022–2032 Employment Projections and WEF Future of Jobs Report 2026. At current growth rates, median salary reaches $115K by 2030.
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The median Nurse Practitioner salary in Amarillo, TX is $115,000 per year as of Q1 2026. This figure represents the midpoint of all reported compensation for this role in the Amarillo–TX metropolitan area, based on data from the Bureau of Labor Statistics Occupational Employment Statistics, H-1B visa disclosures from the Department of Labor, and O*NET occupational data.
Entry-level Nurse Practitioners in Amarillo with 0–2 years of experience typically earn between $95,000 and $115,000 annually. Mid-career professionals with 3–7 years command $115,000 to $138,000, while senior-level practitioners with 8+ years of experience regularly earn $138,000 to $166,000 or more.
Amarillo has a cost of living index of 82 compared to the US national average of 100. This means your salary goes approximately 18% further in Amarillo than the national average. Crucially, Texas has no state income tax — giving Amarillo-based Nurse Practitioners an immediate 5–7% take-home pay advantage over workers in states like California (9.3%) or New York (6.85%).
Master's or DNP; APRN licensure. 15% of these roles offer some remote flexibility.